6.INDUSTRIAL MICROBIOLOGY AND ENZYMOLOGY
- Industrial Microbiology.
- Enzymology
- Role of Microbes in industrial product.
- Growth of Microorganism in controlled environment.
- Study of Microorganism for strain improvement.
- Overview of enzymology and microbial therapeutics enzymes.
- Enzymes in biotechnology.
- Microbial enzymes - Production and purification.
- Application of microbial enzymes.
- Review Paper writing.
- Research Paper Publication.
7. Molecular Docking and Visualization
- Molecular Docking
- Types of docking
- Server and tools for molecular docking and visualization.
- AUTODOCK,
- Fundamentals of Drug discovery and development,
- Target Discovery,
- Lead Identification ,
- Lead Optimization and Validation,
- Pharmacophore Modeling
8. CADD (Computer Aided Drug Designing)
- Computer Aided Drug Designing(PharmacophoreDesign).
- Genomics and Proteomics (Biological Sample).
- Databases (GeneDB,PUBCHEM,DRUGBANK,RCSB,ZINC).
- Structure Based Drug Design (Protein structure Validation).
- Grid Parameter.
- Docking Score Validation.
- Active site Identification using PyMOL.
9. GWAS (Genome Wide Association Studies) .
- Overview on GWAS.
- Bioinformatics and Genomics
- Database and Tools(NCBI,BLAST,PDB etc)
- Blast understanding for large Scale genomic data
- Genome Annotation
- Overview of NGS/GWAS
- Overview on GWAS.
- Bioinformatics and Genomics
- Database and Tools(NCBI,BLAST,PDB etc)
- Blast understanding for large Scale genomic data
- Genome Annotation
- Overview of NGS/GWAS
10.Introduction of Interactive Metagenomics
- Introduction of Interactive Metagenomics
- NCBI taxonomy tree
- Identification of Methylated residue
- Annotation of all CpGA region
- KEGG Pathway
- Methylation Sequence Analysis
- MEGAN Visualization
- Annotation of Metagenomics sequence database
- Command line Tools
11. CAS-9 TECHNOLOGY FOR GENE EDITING
- Scope and application of Molecular Biology
- Computational Biology & Bioinformatics.
- Overview of Genetic Engineering
- Introduction and tools of Genome-editing.
- chronological perception of CRISPR/Cas Technology. gRNA, CAS9, and
CAS-FISH.
- Application of CRISPR/Cas9 Technology.
- Scope and Challenges in CRISPR/Cas9 Technology.
- CRISPR/Cas9 System (CRISPR on-target and off-target analysis).
- CRISPR Technology and Personalized Medicine.
- Next Generation Technology Approach for CRISPR Technology.
- Ethical issues related to CRISPR Technology.
- Review Paper writing.
- Paper Publication.
12. NGS – ( Next Generation Sequencing)
- Overview of NGS
- Data Retrieval And Data type.
- Genomic Bioinformatics
- Genome Visualization
- Database and Tools
- Data Retrieval and Data type
- Alignment read using reference Genome( COBALT, Tophat/Star).
- Genomic Bioinformatics
- Pathway and Gene Ontology
- Genome Variant Detection
13. BIOPYTHON - BASIC
- Biopython - Introduction
- Installation of Biopython.
- Operation in Sequence object
- Translation of Sequence
- Handling Blast output file using Biopython
- Finding percent GC of Sequence
- Parsing Biologoical file format (Fasta,Genebank).
- Understanding of Biopython body structure
- Genome Visualization using Biopython
- DNA/ RNA Proteins sequence operation (Reverse complement of DNA
string)
14. Skill Development Training Program
- Research Proposal.
- Key components for research work.
- Skills of scientific information to write a report.
- Journal & Paper publication process.
- Concept of Impact factor and citation index.
- Scientific approach to write a review paper.
- Evaluation and submission of research paper for publication.
